Clinical Research Publications and Presentations
Published articles by Clinical Research Department staff are listed below. Click on the link to review the Pubmed abstract or free full article where available. Articles on this page are grouped by Recent Publications, Key Publications and Recent Meetings and Clinical Presentations.
Genetics meets environment: evaluating gene-environment interactions in neurologic diseases.
Marras C, Goldman SM. Seminars in Neurology, 31(5):553-61, 2012. PMID: 22266892
Publication Abstract
Genetic Modification of the Association of Paraquat and Parkinson’s Disease.
Goldman SM, Kamel F, Ross GW, Bhudhikanok GS, Hoppine JA, Korell M, Marras C, Meng C, Umbach DM, Kasten M, Chade AR, Comyns K, Richards MB, Sandler DP, Blair A Langston JW, Tanner CM. Movement Disorders, 2012 Oct. PMID: 23045187
Publication Abstract
Brain organochlorines and Lewy pathology: The Honolulu-Asia aging study.
Goldman SM, Kamel F, Ross GW, Bhudhikanok GS, Hoppine JA, Korell M, Marras C, Meng C, Umbach DM, Kasten M, Chade AR, Comyns K, Richards MB, Sandler DP, Blair A Langston JW, Tanner CM. Movement Disorders, 2012 Oct. PMID:22976848 [PubMed - in process]
Publication Abstract
Dopamine transporter imaging is associated with long-term outcomes in Parkinson's disease.
Ravina B, Marek K, Eberly S, Oakes D, Kurlan R, Ascherio A, Beal F, Beck J, Flagg E, Galpern W, Harman J, Lang A, Schwarzschild M, Tanner C, Shoulson I. Mov Disord. 2012 Sep 15;27(11). PMID 22976926.
Publication Abstract
Penetrance of LRRK2 G2385R and R1628P is modified by common PD-associated genetic variants.
Wang C, Cai Y, Zheng Z, Tang BS, Xu Y, Wang T, Ma J, Chen SD, Langston JW, Tanner CM, Chan P; the Chinese Parkinson Study Group (CPSG). Parkinsonism Relat Disord. 2012 Jun 1. PMID: 22658533.
Publication Abstract
Meta-analysis of Parkinson’s disease: identification of a novel locus, RIT2.
Pankratz N, Beecham GW, DeStefano AL, Dawson TM, Doheny KF, Factor SA, Hamza TH, Hung AY, Hyman BT, Ivinson AJ, Krainc D, Latourelle JC, Clark LN, Marder K, Martin ER, Mayeux R, Ross OA, Scherzer CR, Simon DK, Tanner C, Vance JM, Wszolek ZK, Zabetian CP, Myers RH, Payami H, Scott WK, Foroud T; PD GWAS Consortium. Ann Neurol. 2012 Mar;71(3). PMID: 22451204.
Publication Abstract
Head injury, alpha-synuclein Rep1 and Parkinson's disease.
Goldman SM, Kamel F, Ross GW, Jewell SA, Bhudhikanok GS, Umbach D, Marras C, Hauser RA, Jankovic J, Factor SA, Bressman S, Lyons KE, Meng C, Korell M, Roucoux DF, Hoppin JA, Sandler DP, Langston JW, Tanner CM. Annals of Neurology, 2012 Jan;71(1):40-8. PMID: 22275250.
Publication Abstract
Pre-motor features of Parkinson's disease: the Honolulu-Asia Aging Study experience.
Ross GW, Abbott RD, Petrovitch H, Tanner CM, White LR. Parkinsonism Relat Disord. 2012 Jan;18 Suppl 1:S199-202. PMID: 22166434.
Publication abstract
Genetics meets environment: evaluating gene-environment interactions in neurologic diseases.
Marras C, Goldman SM Seminars in Neurology, 2011 31(5):553-61. PMID: 22266892.
Publication abstract
Solvent exposures and parkinson disease risk in twins.
Goldman SM, Quinlan PJ, Ross GW, Marras C, Meng C, Bhudhikanok GS, Comyns K, Korell M, Chade AR, Kasten M, Priestley B, Chou KL, Fernandez HH, Cambi F, Langston JW, Tanner CM. Annals of Neurol. 2011 Nov 14. PMID: 22083847.
Publication abstract
The relation between depression and parkin genotype: The CORE-PD study.
Srivastava A, Tang MX, Mejia-Santana H, Rosado L, Louis ED, Caccappolo E, Comella C, Colcher A, Siderowf A, Jennings D, Nance M, Bressman S, Scott WK, Tanner C, Mickel S, Andrews H, Waters C, Fahn S, Cote L, Frucht S, Ford B, Alcalay RN, Ross B, Orbe Reilly M, Rezak M, Novak K, Friedman JH, Pfeiffer RD, Marsh L, Hiner B, Merle D, Ottman R, Clark LN, Marder K.. Parkinsonism Relat Disord. 2011 Aug 17. [Epub ahead of print] PMID: 21856206.
Publication abstract
Association of DRD2 and DRD3 polymorphisms with Parkinson's disease in a multiethnic consortium.
V. McGuirea, S.K. Van Den Eeden, C.M. Tanner, F. Kamel, D.M. Umbach, K. Marder, R. Mayeux, B. Ritz, G.W. Ross, H. Petrovitch, B. Topol, R.A. Popat, S. Costello, A.D. Manthripragada, A. Southwick, R.M. Myers, L.M. Nelson. Journal of the neurological sciences [0022-510X] McGuire yr:2011 Aug 15 vol:307 iss:1-2 pg:22 -29 PMID: 21663922.
Publication abstract
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
Chuong BD, Tung JY, Dorfman E, Kiefer AK, Drabant EM, Franke U, Mountain JL, Goldman SM, Tanner CM, Langston JW, Wojcicki A, Eriksson N. PLoS Genetics, 2011 Jun;7(6):e1002141. Epub 2011 Jun 23. PubMed Central PMCID: PMC3121750
Publication abstract
A comparison of treatment thresholds in two large Parkinson's disease clinical trial cohorts.
Marras C, Lang AE, Eberly SW, Oakes D, Fahn S, Schwid SR, Hyson C, Shoulson I; Parkinson Study Group DATATOP and PRECEPT investigators. Mov Disord. 2009 Dec 15;24(16) PMID: 19908310.
Publication abstract
Predictors of time to requiring dopaminergic treatment in 2 Parkinson’s disease cohorts.
Marras C, McDermott MP, Marek K, Rochon P, Naglie G, Tanner CM, et. Mov Disord. 2011 Feb 1. Epub ahead of print. PMID: 21287602.
Publication abstract
Coffee, ADORA2A, and CYP1A2: the caffeine connection in Parkinson’s disease.
Popat RA, Van Den Eeden SK, Tanner CM, et al. Eur J Neurol. 2011 Jan 31. Epub ahead of print. PMID: 21281405.
Publication abstract
Rotenone, Paraquat and Parkinson’s Disease.
Tanner CM, Kamel F, Ross GW, Hoppin JA, Goldman SM, Korell M, Marras C, Bhudhikanok GS, Kasten M, Chade AR, Comyns K, Richards M, Meng C, Priestley B, Fernandez HH, Cambi F, Umbach DM, Blair A, Sandler DP, Langston JW. Environ Health Perspect 2011 Jan 26. Epub ahead of print. PMID: 21269927.
Publication abstract
Neuropsychological Profile of Parkin Mutation Carriers with and without Parkinson Disease: The CORE-PD Study.
Caccappolo E, Alcalay RN, Mejia-s=Santana H, Tang MX, Rakitin B, Rosado L, Louis ED, Comella CL, Colcher A, Jennings D, Nance MA, Bressman S, Scott WK, Tanner CM, et al. J Int Neuropsychol Soc. 2011 Jan: 17(1): 91-100. PMID: 21092386.
Publication abstract
Olfaction in Parkin heterozygotes and compound heterozygotes: The CORE-PD study.
Alcalay RN, Siderowf A, Ottman R, Caccappolo E, Mejia-Santana H, Tang MX, Rosado L, Louis E, Ruiz D, Waters C, Fahn S, Cote L, Frucht S, Ford B, Orbe-Reilly M, Ross B, Verbitsky M, Kisselev S, Comella C, Colcher A, Jennings D, Nance M, Bressman S, Scott WK, Tanner C, et al. Neurology. 2011 Jan 25;76(4):312-3. PMID: 21205674.
Publication abstract
Familial aggregation of Parkinson’s disease in a multiethnic community-based case-control study.
Shino MY, McGuire V, Van Den Eeden SK, Tanner CM, et al. Mov Disord. 2010 Nov 15;25 (15): 2587-94. PMID: 20842689.
Publication abstract
Exploring the electrocardiogram as a potential tool to screen for premotor Parkinson’s disease.
Valappil RA, Black JE, Broderick MJ, Carrillo O, Frenette E, Sullivan SS, Goldman SM, Tanner CM, Langston JW. Mov Disord. 2010 Oct 30;25(14): 2296-303. PMID: 20976736.
Publication abstract
Comorbid cancer in Parkinson’s disease.
Lo RY, Tanner CM, Van Den Eeden SK, et al. Mov Disord. 2010 Sep 15;25(12): 1809-17. PMID: 20669266.
Publication abstract
Cancer incidence in a trial of an antiapoptotic agent for Parkinson’s disease.
Schwid SR, Bausch J, Oakes D, Schuchter L, Tanner C, et al. Mov Disord. 2010 Sep 15;25(12): 1801-8. PMID: 20669311.
Publication abstract
Frequency of known mutations in early-onset Parkinson disease: implication for genetic counseling: the consortium on risk for early onset Parkinson disease study.
Alcalay RN, Caccappolo E, Mejia-Santana H, Tang MX, Rosado L, Ross BM, Verbitsky M, Kisselev S, Louis ED, Comella C, Colcher A, Jennings D, Nance MA, Bressman SB, Scott WK, Tanner C, et al. Arch Neuro. 2010 Sep; 67(9): 1116-22. PMID: 20837857.
Publication abstract
Late-life hemoglobin and the incidence of Parkinson’s disease.
Abbott RD, Ross GW, Tanner CM, et al. Neurobiol Aging. 2010 Aug 13. (Epub ahead of print) PMICD:PMC3006667.
Publication abstract
Teaching program for the Movement Disorder Society-sponspored revision of the Unified Parkinson’s Disease Rating Scale: (MDS-UPDRS).
Goetz CG, Stebbins GT, Chmura TA, Fahn S, Poewe W, Tanner CM. Mov Disord. 2010 Jul 15; 25(9): 1190-4. PMID: 20629138.
Publication abstract
Predictors of Parkin mutations in early-onset Parkinson disease: the consortium on risk for early-onset Parkinson disease study.
Marder KS, Tang MX, mejia-Santana H, Rosado L, Louis ED, Comella CL, Colcher A, Siderowf AD, Jennings D, Nance MA, Bressman S, Scott WK, Tanner CM, et al. Arch Neurol. 2010 Jun; 67(6): 731-8. PMID: 20558392.
Publication abstract
Trichloroethylene and Parkinson's disease: dissolving the puzzle.
Goldman SM. Expert Rev Neurother. 2010 Jun;10(6):835-7. PMID: 20518596.
Publication abstract
Reliability and Validity of Two Self-administered Questionnaires for Screening Restless Legs Syndrome in Population-based Studies.
Popat RA, Van Den Eeden SK, Tanner CM, et al. Sleep Med. 2010 Feb; 11(2): 154-60. PMID: 20089446.
Publication abstract
Self-report of Cognitive Impairment and Mini-mental State Examination Performance in PRKN, LRRK2, and GBA Carriers with Early Onset Parkinson’s disease.
Alcalay RN, Mejia-Santana H, Tang MX, Rakitin B, Rosado L, Ross B, Verbitsky M, Kisselev S, Louis ED, Comella CL, Colcher A, Jennings D, Nance MA, Bressman S, Scott WK, Tanner C, et al. J clin Exp Neuropsychol. 2010 Feb 24: 1-5. PMID: 20182943.
Publication abstract
Urate as a Predictor of the Rate of Clinical Decline in Parkinson Disease.
Ascherio A, Lewitt PA, Xu K, Eberly S, Watts A, Matson WR, Marras C, Kieburtz K, Rudolph A, Bogdanov MB, Schwid SR, Tennis M, Tanner CM, Beal MF, Lang AE, Oakes D, Fahn S, Shoulson I, Schwarzschild MA; for the Parkinson Study Group DATATOP Investigators. Arch Neurol. 2009 Dec;66(12): 1460-8. Epub. PMID: 19822770.
Publication abstract
Motor Phenotype of LRRK2 G20195S carriers in early onset PD.
Alcalay R, Clark L, Mejia-Santana H, Tang M, Rosado L, Louis E, Comella C, Colcher A, Jennings D, Nance M, Bressman S, Scott W, Tanner C, et al. Arch Neurol. 2009 Dec; 66(12): 1517-22. PMID: 20008657.
Publication abstract
Health Related Quality of Life in Early Parkinson’s Disease: Impact of Motor and Non-motor Symptoms, Results from Chinese Levodopa Exposed Cohort.
Qin Z, Zhang L, Sun F, Fang X, Meng C, Tanner C, Chan P; the Chinese Parkinson Study Group. Parkinsonism Relat Disord. 2009 Dec; 15(10): 767-771. Epub 2009 Jun 23. PMID: 19553154.
Publication abstract
Clinical Features in Early Parkinson Disease and Survival.
Lo RY, Tanner CM, Albers KB, Leimpeter AD, Fross RD, Bernstein AL, McGuire V, Quesenberry CP, Nelson LM, Van Den Eeden SK. Arch Neurol. 2009 Nov; 66(11): 1353-8. PMID: 19901166.
Publication abstract
A Longitudinal Program for Biomarker Development in Parkinson’s disease: a feasibility study.
Ravina B, Tanner C, Dieuliis D, Eberly S, Flagg E, Galpern WR, Fahn S, Goetz Shoulson I; Parkinson Study Group LABS-PD Investigators. Mov Disord. 2009 Oct 30; 24(14): 2081-90. PMID: 19691116.
Publication abstract
Occupation and risk of parkinsonism: a multicenter case-control study.
Tanner CM, Ross GW, Jewell SA, Hauser RA, Jankovic J, Factor SA, Bressman S, Deligtisch A, Marras C, Lyons KE, Bhudhikanok GS, Roucoux DF, Meng C, Abbott RD, Langston JW. Arch Neurol. 2009 Sep; 66(9): 1106-13. PMID: 19752299.
Publication abstract
Dietary intake in adults at risk for Huntington disease: analysis of PHAROS research participants.
Marder K, Zhao H, Eberly S, Tanner CM, Oakes D, Shoulson I; Huntington Study Group. Neurology. 2009 Aug 4;73(5):385-92. PMID: 19652143.
Publication abstract
Bowel movement frequency in late-life and sunstantia nigra neuron density at death.
Petrovitch H, Abbott RD, Ross GW, Nelson J, Masaki KH, Tanner CM, Launer LJ, White LR. Mov Disord. 2009 Feb 15;24(3): 371-6. PMID: 20518596.
Publication abstract
Meeting Report: Consensus Statement—Parkinson’s Disease and the Environment: Collaborative on Health and the Environment and Parkinson’s Action Network (CHE PAN) Conference 26–28 June 2007.
Jeff Bronstein,1 Paul Carvey,2 Honglei Chen,3 Deborah Cory-Slechta,4 Donato DiMonte,5 John Duda,6 Paul English,7 Samuel Goldman,5 Stephen Grate,8 Johnni Hansen,9 Jane Hoppin,3 Sarah Jewell,5 Freya Kamel,3 Walter Koroshetz,10 James W. Langston,5 Giancarlo Logroscino,11 Lorene Nelson,12 Bernard Ravina,13 Walter Rocca,14 George W. Ross,15 Ted Schettler,16 Michael Schwarzschild,17 Bill Scott,18 Richard Seegal,19 Andrew Singleton,20 Kyle Steenland,21 Caroline M. Tanner,5 Stephen Van Den Eeden,22 and Marc Weisskopf23. Environ Health Perspect. 2009 January; 117(1): 117–121. PMID: 19165397.
Publication abstract
Use of antihypertensives and the risk of Parkinson disease.
Ascherio A, Tanner CM. Neurology. 2009 Apr 15;70(16 Pt 2):1438-44. PMID: 19204275.
Publication abstract
Research priorities in spasmodic dysphonia.
Ludlow CL, Adler CH, Berke GS, Bielamowicz SA, Blitzer A, Bressman SB, Hallett M, Jinnah HA, Juergens U, Martin SB, Perlmutter JS, Sapienza C, Singleton A, Tanner CM, Woodson GE. Otolaryngol Head Neck Surg. 2008 Oct; 139(4): 495-505. PMID: 18922334.
Publication abstract
Nicotine and Parkinson’s disease: Implications for therapy.
Quik M, O’Leary K, Tanner CM.. Mov Disord 2008. PMID: 18683238.
Publication abstract
Association of Olfactory Dysfunction with Risk for Future Parkinson’s Disease.
Ross GW, Petrovitch H, Abbott RD, Tanner CM, Popper J, Masaki K, Launer L, White LR. Ann Neurol 2008;63(2):167-173. PMID: 18067173.
Publication abstract
Predictors of deterioration in health-related quality of life in Parkinson’s disease: Results from the DATATOP trial.
Marras C, McDermott MP, Rochon PA, Tanner CM, Naglie G, Lang AE, Parkinson Study Group DATATOP Investigators. Mov Disord 2008;23(5):653-659. PMID: 18076084.
Publication abstract
Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030.
Dorsey ER, Constantinescu R, Thompson JP, Biglan KM, Holloway RG, Kieburtz K, Marshall FJ, Ravina RM, Schifitto G, Siderowf A, Tanner CM. Neurology 2007;68(5):384-386. PMID: 17082464.
Publication abstract
The G2019S mutation in the Leucine Rich Repeat Kinase 2 gene is not associated with multiple system atrophy.
Ozelius LJ, Foroud T, May S, Senthil G, Sandori P, Low PA, Reich S, Colcher A, Stern MB, Ondo WG, Jankovic J, Huang N, Tanner CM, Novak P, Gilman S, Marshall FJ, Wooten GF, Chelimsky TC, Shults CW, and the North American Multiple System Atrophy Study Group. Movement Disorders 2007; 22(4):546-549. PMID: 17230458.
Publication abstract
Parkin gene variations and parkinsonism: Association does not imply causation.
Langston JW, Tanner CM, Schule B. Ann Neurol. 2007;61(1):4-6. PMID: 17262853.
Publication abstract
Chronic low-level pesticide exposure and neurological function: A population-based study..
Klein C, Kasten M, Schade G, Ehlers J, Raspe H, Tanner CM, Walker G, Heinzow B, Vieregge P. Lancet Neurology 2007: submitted.
DLB and PDD Boundary Issues: Diagnosis, Treatment, Molecular Pathology and Biomarkers. .
Lippa CF, Duda JE, Grossman M, Hurtig HI, Aarsland D, Boeve BF, Brooks DJ, Dickson DW, DuboisB, Emre M, Fahn S, Farmer JM, Galasko D, Galvin JE, Goetz CG, Growdon JH, Gwinn-Hardy KA, Hardy J, Heutink P, Iwatsubo T, Kosaka K, Lee VM-Y, Leverenz JB, Masliah E, McKeith IG, Nussbaum RL, Olanow CW, Ravina BM, Singleton AB, Tanner CM, Trojanowski JQ, Wszolek ZK. Neurology 2007;68:812-819. PMID: 17353469.
Publication abstract
Pesticide exposure and self-reported Parkinson’s disease in the agricultural health study. .
Kamel F, Tanner C, Umbach D, Hoppin J, Alavanja M, Blair A, Comyns K, Goldman S, Korell M, Langston J, Ross G, Sandler D. Am J Epidemiology 2007;165(4):364-365. PMID: 17116648.
Publication abstract
Bowel movement frequency in late-life and incidental Lewy bodies..
Abbott RD, Ross GW, Petrovitch H, Tanner CM, Davis DG, Masaki KH, Launer LJ, Curb JD, White LR. Mov Disord. 2007; 22(11):1581-1586. PMID: 17523195.
Publication abstract
Effect on non-steroidal anti-inflammatory medications on the risk of amyotrophic lateral sclerosis..
Popat RA, Tanner CM, Van Den Eeden SK, Bernstein AL, Bloch DA, Leimpeter A, McGuire V, Nelson LM. Amyotroph Lateral Scler 2007; 8(3):157-163. PMID: 17538777.
Publication abstract
Pramipexole in Levodopa-treated Parkinson Disease Patients of African, Asian, and Hispanic Heritage..
Parkinson Study Group, Tanner CM corresponding author. Clinical Neuropharmacology 2007; 30(2):72-85. PMID: 17414939.
Publication abstract
Minimum Incidence of Primary Cervical Dystonia in a Multiethnic Health Care Population. .
Marras C, Van Den Eeden SK, Fross RD, Benedict-Albers KS, Klingman J, Leimpeter AL, Nelson LM, Risch N, Karter AJ, Bernstein MD, Tanner CM. Neurology 2007;69(7):676-680. PMID: 17698789.
Publication abstract
Potential outcome measures and trial design issues for multiple system atrophy..
May S, Gilman S, Sowell BB, Thomas RG, Stern MB, Colcher A, Tanner CM, Huang N, Novak P, Reich SG, Ondo WG, Low PA, Sandroni P, Lipp A, Marshall FJ, Wooten F, Shults CW; North American Multiple System Atrophy Study Group. Movement Disord. 2007;22(16);2371-2377. PMID: 17914727.
Publication abstract
Mixed lineage kinase inhibitor CEP-1347 fails to delay disability in early Parkinson disease..
The Parkinson Study Group PRECEPT Investigators, Tanner CM (Data Monitoring Committee). Neurology 2007;69(15):1480-1490. PMID: 17881719.
Publication abstract
Epidemiology of Parkinson's disease..
Kasten M, Chade A, Tanner CM. Handb Clin Neurol. 2007;83:129-51. (in process). PMID: 20529301.
Publication abstract
Effect of Reproductive Factors and Postmenopausal Hormone Use on the Risk of Amyotrophic Lateral Sclerosis..
Popat RA, Van Den Eeden SK. Tanner CM, Bernstein AL, Bloch DA, Leimpeter A, McGuire V, Nelson LM. Neuroepidemiology 2006;27(3):117-121. PMID: 16946622.
Publication abstract
A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease.. PMID: 16481597.
NINDS NET-PD Investigators, Tanner CM contributing author. Neurology 2006; 66(5): 664-671.
Publication abstract
Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson’s disease: a large-scale international study..
Elbaz A, Nelson LM, Payami H, Ioannidis JP, Fiske BK, Annesi G, Carmine Belin A, Factor SA, Ferrarese C, Hadjigeorgiou GM, Higgins DS, Kawakami H, Kruger R, Marder KS, Mayeux RP, Mellick GD, Nutt JG, Ritz B, Samii A, Tanner CM, Van Broeckhoven C, Van Den Eeden SK, Wireefeldt K, Zabetian CP, Dehem M, Montimurro JS, Southwick A, Myers RM, Trikalinos TA. Lancet Neurol. 2006; 5(11):917-023. PMID: 17052658.
Publication abstract
Nongenetic causes of Parkinson’s disease..
Chade AR, Kasten M, Tanner CM. J Neural Transm Suppl. 2006;(70):147-151. PMID: 17017522.
Publication abstract
Association of olfactory dysfunction with incidental Lewy bodies..
Ross GW, Abbott RD, Petrovitch H, Tanner CM, Davis DG, Nelson J, Markesbery WR, Masaki K, Launer L, White LR. Movement Disorders. Movement Disorders 2006;21(12):2062-2067 PMID: 16991138.
Publication abstract
Inter-rater Reliability in Application of the Unified Multiple System Atrophy. Movement Disorder.
Shults CW, May S, Tanner CM, Sandroni P, Low PA, Lipp A, Reich SG, Colcher A, Stern MB, Ondo WG, Jankovic J, Huang N, Novak P, Gilman S, Marshall FJ, Wooten GF, Chelimsky TC, Song D, Racette B, Wenning GK, Thomas R. (In Press).
At Risk for Huntington Disease. The PHAROS (Prospective Huntington At Risk Observational Study) Cohort Enrolled..
The Huntington Study Group PHAROS Investigators, Tanner CM contributing author. Arch Neurol 2006;63:991-998. PMID: 16831969.
Publication abstract
Head Injury and Parkinson’s Disease Risk in Twins..
Goldman SM, Tanner CM, Oakes D, Bhudhikanok GS, Gupta A, Langston JW. Annals of Neurology 2006;60:65-72. PMID: 16718702.
Publication abstract
Optimizing the ongoing search for new treatments for Parkinson disease: using futility designs..
Tilley BC, Palesch YY, Kieburtz K, Ravina B, Huang P, Elm JJ, Shannon K, Wooten GF, Tanner CM, Goetz GC; NET-PD Investigators. Neurology 2006;66(5):628-633. PMID: 16534099.
Publication abstract
High-dosage vitamin E supplementation and all-cause mortality..
Marras C, Lang AE, Oakes D, McDermott MP, Kieburtz K, Shoulson I, Tanner CM, Fahn S. Ann Intern Med. 2005; 143(2):152-3; author reply 156-158. PMID: 16027463.
Publication abstract
Verification of self- report of zygosity determined via DNA testing in a subset of the NAS-NRC twin registry 40 years later..
Reed T, Plassman BL, Tanner CM, Dick DM, Rinehart SA, Nichols WC. Twin Res Hum Genet. 2005; 8(4):362-367. PMID: 16176721.
Publication abstract
The North American Multiple System Atrophy Study Group..
Gilman S, May SJ, Shults CW, Tanner CM, Kukull W, Lee VM, Masliah E, Low P, Sandroni P, Trojanowski JQ, Ozelius L, Foroud T; and The North American Multiple System Atrophy Study Group. J Neural Transm 2005;12(12):1687-1694. PMID: 16284910.
Publication abstract
Non-linearity of Parkinson's disease progression: implications for sample size calculations in clinical trials..
Guimaraes P, Kieburtz K, Goetz CG, Elm JJ, Palesch YY, Huang P, Ravina B, Tanner CM, Tilley BC. Clinical Trials 2005;2(6):509-518. PMID: 16422311.
Publication abstract
The Quality of Life in Essential Tremor Questionnaire (QUEST): Development and Initial Validation..
Tröster AI, Pahwa R, Fields JA, Tanner CM, Lyons KE: Parkinsonism Related Disorder 2005;11(6):367-373. PMID: 16103000.
Publication abstract
Excessive Daytime Sleepiness and subsequent development of Parkinson’s Disease..
Abbott RD, Ross GW, White LR, Tanner CM, Masaki KH, Nelson JS, Curb JD, Petrovitch H: Neurology 2005;65(9):1442-1446. PMID: 16275833.
Publication abstract
Effect of Reproductive Factors and Postmenopausal Hormone Use on the Risk of Parkinson’s Disease..
Popat RA, Van Den Eeden SK, Tanner CM, McGuire V, Bernstein AL, Block DA, Leimpeter A, Nelson LM. Neurology 2005;65(3):383-390. PMID: 16087902.
Publication abstract
Occupation and parkinsonism in three movement disorders clinics..
Goldman SM, Tanner CM, Olanow CW, Watts RL, Field RD, Langston JW. Neurology 2005;65(9):1430-1435. PMID: 16162857.
Publication abstract
Survival in Parkinson disease: thirteen-year follow up of the DATATOP cohort..
Marras C, McDermott MP, Rochon PA, Tanner CM, Naglie G, Rudolph A, Lang AE, Parkinson Study Group. Neurology 2005;64(1):87-93. PMID: 15642909.
Publication abstract
Smell identification ability in twin pairs discordant for Parkinson’s disease.. PMID: 15719425.
Marras C, Goldman S, Smith A, Barney P, Aston D, Comyns K, Korell M, Langston JW, Ross GW, Tanner CM. Movement Disorders 2005;20(6):687-693.
Publication abstract
Consumption of milk and calcium in midlife and the future risk of Parkinson disease. . PMID: 15781824.
Park M, Ross GW, Petrovitch H, White LR, Masaki KH, Nelson JS, Tanner CM, Curb JD, Blanchette PL, Abbott RD. Neurology 2005;64(6):1047-1051.
Publication abstract
A responsive outcome for Parkinson’s disease neuroprotection futility studies.. PMID: 15668964.
Elm JJ, Goetz CG, Ravina B, Shannon K, Wooten GF, Tanner CM, Palesch YY, Huang P, Guimaraes P, Kamp C, Tilley BC, Kieburtz K. Annals of Neurology 2005; 57(2): 197-203.
Publication abstract
KEY PUBLICATIONS
DATATOP: a multi-center clinical trial in early Parkinson’s disease.
Parkinson Study Group. Arch Neurol 1989;46:1052-1060.
Environmental factors and Parkinson’s disease: a case control study in China.
Tanner CM, Chen B, Wong W, Peng M, Liu Z, Liang X, Kao LC, Gilley DW, Goetz CG, Schoenberg BS. Neurology 1989;39:660-664. PMID: 2710356.
Publication abstract
Parkinson’s disease in twins: An etiologic study.
Tanner CM, Ottman R, Goldman SM, Ellenberg J, Chan P, Mayeux R, Langston JW: JAMA 1999;281(4):341-46. PMID: 9929087.
Publication abstract
Epidemiology of Movement Disorders.
Tanner CM, Goldman SM. Current Opinion in Neurology 1994;7:340-345. PMID: 7952243.
Publication abstract
The Association of Coffee and Caffeine Intake with the Risk of Parkinson’s Disease.
Ross GW, Abbott RD, Petrovich H, Morens DM, Grandinetti A, Tung KH, Tanner CM, Masaki KH, Blanchette PL, Curb, JD, White LR, Popper J. JAMA 2000: 283(20):2674-2679. PMID: 10819950.
Publication abstract
Essential tremor in twins: An assessment of genetic vs. environmental determinants of etiology.
Tanner CM, Goldman SM, Lyons KE, Aston DA, Tetrud JW, Welsh MD, Langston JW, Koller WC. Neurology 2001; 57(8):1389-1391. PMID: 11673577.
Publication abstract
Smoking and Parkinson’s disease in twins.
Tanner CM, Goldman SM, Aston D, Ottman R, Ellenberg J, Mayeaux R, Langston JW. Neuorology 2002; 58(4): 581-588. PMID: 11865136.
Publication abstract
Incidence of Parkinson’s disease (PD): Variations by age, gender and race/ethnicity.
Van Den Eeden SK, Tanner CM, Bernstein AL, Fross RD, Leimpeter A, Bloch DA, Nelson LM. Am J Epidemiol 2003; 157(11):1015-1022. PMID: 12777365.
Publication abstract
Is the cause of Parkinson’s disease environmental or hereditary? Evidence from twin studies.
Tanner CM. Advances in Neurology 2003;91:133-142. PMID: 12442672.
Publication abstract
RECENT MEETINGS AND CLINICAL PRESENTATIONS
Rotenone, Paraquat and Parkinson’s Disease (PD).
Tanner CM, Kamel F, Ross GW, Hoppin JA, Goldman SM, Korell M, Marras C, Bhudhikanok G, Kasten M, Chade A, Comyns K, Meng C, Priestley B, Fernandez HH, Cambi F, Umbach D, Blair A, Sandler DP, Langston JW. Annals of Neurology 2010; 68 Suppl 14): S17.
Depression among Carriers and Non Carriers of Parkin Mutations.
Srivastava Anil, Tang Ming, Louis Elan, Mejia-Santana Helen, Ottman Ruth, Rosado Llency, Marder Karen, Commela Cynthia, Bressman Susan, Nance Martha, Siderowf Andrew, Jennings Danna, Colcher Amy, Scott William, Waters Cheryl, Cote Lucien, Andrews Howard, Tanner Caroline, et al. Neurology 2010; 74(9) Suppl 2: S08.005.
Parkinson’s Disease Risk is Increased in Discordant Twins Exposed to Specific Solvents.
Goldman Samuel.M, Tanner Caroline.M, Meng Cheryl, et al. Neurology 2010; 74(9) Suppl 2: S03.005.
Late-life Hemoglobin and the Incidence of Parkinson’s Disease: The Honolulu- Asia Aging Study.
Petrovitch Helen, Abbott Robert, Ross Web, Tanner Caroline, et al. Neurology 2010; 74(9) Suppl 2: S03.004.
Parkinson’s Disease (PD) Increases Risk for Mild Cognitive Impairment (MCI).
Adler Charles.H, Hentz Joseph.G, Shill Holly A, Sabbagh Marwan. N, Connor Donald.J, Evidente Virgilio Gerald, Driver-Dunckley Erika, Tanner Caroline, et al. Neurology 2010; 74(9) Suppl 2: P01.218.
Follow-up of Persons with Neurologic Diseases (Found): Remote Follow-up- A Practical Approach To Maintain Continuous Contact.
Tanner Caroline.M; Meng Cheryl.C, Shoulson Ira, et al. Neurology 2010; 74(9) Suppl 2: P01.163
Relationship of Brain Organochlorine Levels with Lewy Pathology: The Honolulu- Asia Aging Study.
Ross Web, Duda John E, Petrovitch Helen, Pellizzari Edo, He Qimei, Miller Diane B, O’Callaghan James P, Tanner Caroline M, et al. Neurology 2010; 74(9) Suppl 2: P01.157.
Can the EKG be used to identify prodromal PD? Assessment of heart rate variability (HRV) during wakefulness in patients with RBD.
Valappil R, Black J.E, Broderick M.J, Carrillo O, Frenette E, Sullivan S, Tanner CM, Langston JW. Movement Disorders 2009, Vol.24, suppl. 1: u-234
A longitudinal program for biomarker development in parkinson's disease.
Ravina B, Tanner C, DiEuliis D, Flagg E, Shoulson I, Parkinson Study Group, LABS-PD Investigators (Rochester, New York). Movement Disorders 2009, Vol.24, suppl. 1: We-192
Motor Phenotype of LRRK2 G20195S carriers in early onset PD.
Alcalay R, Clark L, Mejia-Santana H, Tang M, Rosado L, Louis E, Comella C, Colcher A, Jennings D, Nance M, Bressman S, Scott W, Tanner C, et al. Movement Disorders 2009, Vol.24, suppl. 1: Mo-86
Demographic and Clinical Characteristics of LRRK2 G2019S Carriers in Early Onset PD.
Alcalay Roy N, Clark Lorraine N, Mejia-Santana Helen, Tang Ming, Rosado Llency E, Louis Elan, Comella Cynthia, Colcher Amy, Jennings Danna, Nance Martha, Bressman Susan, Scott William K, Tanner CM, et al. Neurology 2009; 72(11) Suppl 3: P08.095
Late-life Cognitive Function in Non-Demented Disease. .
Ross G. W, Abbott Robert D, Petrovitch Helen, Tanner CM, Masaki Kamal, White Lon R. Neurology 2009; 72(11) Suppl 3:P04.020
Smoking, Genes and Risk for Parkinson’s Disease. .
Gu zhuqin, Tanner CM, Chan Piu.. Neurology 2009; 72(11) Suppl 3: P09.012
Minimum Incidence of Primary Spasmodic Dysphonia.
Lo RY, Tanner CM, Albers KB, Leimpeter AD, Fross RD, Comyns K, Liang G, Bernstein AL, Klingman J, Goldman S, Ozelius L, Marras C, Bressman SB, Comella CL, Risch N, Nelson LM, Ludlow CL, McGee BS, Van Den Eeden SK. Neurology 2009; 72(11) Suppl 3: A273
Late-Life Cognitive Function in Non-Demented Elderly Men and the Incidence of Parkinson’s Disease.
Ross GW, Abbott RD, Petrovitch H, Tanner CM, Masaki K, White LR. Neurology 2009; 72(11) Suppl 3: A170
Demographic and Clinical Characteristics of LRRK2 G2019S Carriers in Early Onset PD.
Alcalay RN, Clark LN, Mejia-Santana H, Tang M, Rosado LE, Luis E, Comella C, Colcher A, Station M, Jennings D, Nance M, Bressman S, Scott WK, Tanner C, Micket S, Andrews H, Waters C, Fahn S, Ross BM, Cote LJ, Frucht S, Rezak M, Novak K, Friedman J, Pfeiffer R, Marsh L, Caccappolo EZ, Hiner B, Siderowf A, Ottman R, Marder K. Neurology 2009; 72(11) Suppl 3: A389
The Effect of Cigarette Smoking on Survival in Parkinson’s Disease.
Van Den Eeden SK, Albers KB, Nelson LM, Lo R, Leimpeter AD, Quesenberry CP, Bernstein AL, McGuire V, Tanner CM. Neurology 2009; 72(11) Suppl 3: A450
Smoking , Genes and Risk for Parkinson’s Disease
Gu Z, Tanner C, Chan P.. Neurology 2009; 72(11) Suppl 3: A450
a-Synuclein (SNCA) Genotype Modifies the Association between Head Injury and Parkinson’s Disease (PD).
Goldman SM, Kamel F, Bhudhikanok G, Korell M, Sterling L, Hoppin J, Umbach D, Ross GW, Sandler DP, Blair A, Langston JW, Tanner CM. Neurology 2009; 72(11) Suppl 3: A258
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